Is there a difference between treating with prednisone and dexamethasone? This Italian study examines the question by comparing two prospective series of patients treated with HD-DEX with historical controls. The response rate in the two studies were very good. This figure (1A) shows the fate of the 33 responders out of the 37 in the study. 58% of the responders maintained their reponse at 50 months.
EDTA-dependent pseudo-thrombocytopenia
Large Spanish population study, showing that 0.15% of 20000 individuals have pseudo-thrombocytopenia.
Then this Italian study showed that, at their center, 15% of patients referred for asymptomatic thrombocytopenia has pseudo.
The causative antibodies can be of IgG, IgM or, most commonly, IgG. Some 20% have no detectable antibodies. There is no correlation with lymphoproliferative disease. Study here.
Soluble transferrin receptor. This test is rarely used. The reference interval is a little shifty, but this Finnish study in Blood from 1998 pinned it 1.3-3.3.
Staging
Prognosis
Treatment
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